Tofranil (the brand title for Imipramine) is a drug related to antidepressants of the tricyclic class. It is available in online pharmacies the form of tablets, solution for insertion into the muscle. You can buy Tofranil no prescription pills online in the strengths of 25, 50 and 75 mg.
Tofranil increases the levels of dopamine, serotonin and norepinephrine between synapses, which leads to an increase in their activity. In addition, the drug blocks M-cholinergic receptors and alpha-adrenoreceptors. As a result of the these effects properties, Tofranil provides the moderately expressed sedative effect, reduces the feeling of anguish, anxiety, improves mood, relieves motor retardation.
Reasons to buy Tofranil online
The effect of Tofranil has an accumulative nature – the effect begins to appear after two to eight weeks. The speed of occurrence of the first effects in all people is different and depends on the individual characteristics of a patient’s body and individual tolerability. You can get this effective drug, even if you are living in the small town where it is hard to buy Tofranil without a prescription. It is even possible to buy Tofranil online overnight, without the necessity to wait for the life-saving drug for many days. Buy Tofranil only from the trusted legal drugstores online.
Tofranil: uses and indications
Since the beginning of the 2000s, Tofranil pills have been widely used in the psychiatric practice. Tofranil is used for the treatment of such indications and uses:
- panic attacks;
- neurotic depressive conditions;
- depressive symptoms in psychopathies;
- depression of various genesis, including alcoholic, climacteric, reactive and endogenous;
- atypical depressive conditions;
- bipolar disorder in the phase of depression;
- asthenic depressive syndrome;
- night incontinence of urine of a functional nature in children.
Tofranil is taken strictly according to the doctor’s prescription with strict observance of dosages and rules of application of the drug.
Tofranil: dosage instructions
Tofranil no prescription treatment always starts with the minimum dosage effective for a particular patient. During the first two weeks, the dose of the drug is gradually increased until a full-fledged clinical effect appears, after achieving the desired goal, the dosage is reduced to a level sufficient to maintain the effect. For adults, prescribe from 25 to 50 mg of the drug, 3-4 times a day, orally. Dosage for children from 6 to 12 years is 10 to 30 mg per day, divided into 2 doses. For children from 12 years, you can appoint up to 50 mg of Tofranil per day, twice a day.
The special attention is needed when taking Tofranil in patients who have ever had suicidal attempts or expressed thoughts of suicide, if the patient is on out-patient treatment, relatives and friends will be warned by the doctor about the need to monitor the patient and immediately seek medical advice in the event of a change in the patient’s behavior. Treatment for maintenance dosage is performed for at least six months.
Tofranil: side effects and contraindications
Like any pharmacologically active drug, Tofranil has a list of contraindications that must be taken into account when deciding on the choice of a medicine. These contraindications include:
- ischemic heart disease;
- severe liver and kidney pathologies in the stage of failure;
- epilepsy and other diseases, in which the development of convulsive syndrome is possible;
- mental disorders in the form of schizophrenia, manic manifestations;
- the period of treatment with antidepressants belonging to the group of monoamine oxidase inhibitors;
- conduction disorders of the heart;
- arrhythmic conditions;
- eye diseases associated with increased intraocular pressure;
- impaired urinary excretion;
- pregnancy and lactation.
Tofranil without a prescription is allowed or giving to children from 6 years old with the aim of treating bed-wetting incontinence. In other cases, the drug is prescribed only at 18 years of age. The ban on the use of the drug during pregnancy and lactation is due to the fact that the active substance is able to pass through the placental barrier, which leads to an effect on the developing fetus, and to be excreted in breast milk, getting into the child’s body. Getting into the child’s body of the active substance in both cases is extremely undesirable.
Side effects of Tofranil include:
- heart rhythm disturbances;
- spasms of peripheral vessels,
- hair loss;
- increased sensitivity to exposure to sunlight;
- urinary disorders;
- inflammatory liver damage;
- nausea and vomiting.
Barbiturates reduce the plasma concentration of the substance. Cheap Tofranil, when combined with drugs that depress the work of CNS, ethyl alcohol, increases their side effects, the pressure may drop significantly and respiratory depression may increase. Combined intake of substance with MAO inhibitors significantly increases the risk of seizures, hyperthermia, psychomotor agitation, coma. Simultaneous administration of the drug with anticholinergic drugs leads to an additive anticholinergic effect. The drug is contraindicated in the first trimester of pregnancy. It is not prescribed to nursing women.