Category Archives: Sleeping Pills

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Nitrazepam is an effective hypnotic medicine from the benzodiazepine group. It possesses anticonvulsant, calming and muscle relaxant action.

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Indications for use

Buy Nitrazepam Mogadon 5mgThis drug is used to manage sleep problems of various genesis (trouble falling asleep, recurrent early awakenings), somnambulism, various forms of convulsive seizures (including Vest syndrome), organic lesions of the CNS, mental disorders, accompanied by an increased sense of stress and anxiety, encephalopathy with epileptic manifestations, abstinence syndrome associated with alcoholism or addiction to drugs, schizophrenia (as part of combination therapy).

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The main contraindications for usage of Nitrazepam include: acute depression, severe respiratory failure, drug or alcohol addiction, severe alcohol intoxication, temporal epilepsy, acute intoxication with medicine that can express an inhibitory effect on the CNS, pregnancy and breast-feeding, allergic reaction to the components of the medicine or other drugs of this group.

Relative contraindications: cerebral as well as spinal ataxia, organic diseases of the brain, nocturnal sleep apnea, ataxia, respiratory failure, psychosis, tendency to abuse of psychoactive drugs, elderly age.

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Pharmacologic Action

buy nitrazepam onlineThe hypnotic effect of Nitrazepam is characterized through the inhibition of specific cells from the reticular cluster of the brain stem. It diminishes the impact of sensitive, vegetative and motor stimuli, which break the system of healthy asleep.

Under the influence of Nitrazepam, the depth and duration of sleep increases. Sleep and awakening proceed physiologically.

The anxiolytic effect of Nitrazepam is due to the action on the limbic system and is manifested through the reduction of emotional tension, alleviation of anxiety, fear, and nervousness.

The action of Nitrazepam begins 30 minutes after intake and lasts for about 6 hours.

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Adverse effects

Like with any other medicine of this type, there is possibility for manifestation of the following adverse effects:

  • Sleepiness (usually for older people or at the start of treatment),
  • tiredness,
  • lightheadedness,
  • inability to concentrate,
  • ataxia,
  • difficulties walking straight,
  • gait disturbance,
  • stupor,
  • dullness of emotions,
  • decrease in speed of mental and physical reactions,
  • headache,
  • excitement,
  • sadness,
  • tremble,
  • overall low mood,
  • anterograde amnesia,
  • uncertainty,
  • weakness,
  • myasthenia gravis,
  • paradoxical reactions (hostile outbursts, suicidal behavior, muscle spasm, confusion, hallucinations, acute arousal, touchiness, anxiety, sleeplessness),
  • anemia,
  • dry mouth,
  • indigestion,
  • nausea,
  • problems with appetite,
  • violations of liver function,
  • jaundice,
  • changes in libido,

Allergic reactions to Nitrazepam components: hives, itching.

Other negative manifestations may include: addiction, drug dependence; hypotension; rarely – oppression of the respiratory center, impaired vision, bulimia, weight changes, tachycardia. When reducing the dose abruptly or upon discontinuation of administration – withdrawal syndrome that includes bad temper, headache, tension, anxiety, fear, tenseness, sleep problems, dysphoria, vomiting, shiver, perceptual disorders, tachycardia, convulsions, hallucinations, rarely – acute psychosis.

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Nitrazepam (Mogadon) Overdose

Manifestations of overdose include: tiredness, decreased reflexes, deafness, decreased reaction to painful stimulation, deep sleep, dysarthria, ataxia, sight problems, shivers, shortness of breath, intense weakness, hypotension, collapse , oppression of cardiac and respiratory action, coma.

Treatment includes gastric lavage, forced diuresis and activated charcoal. Also should be used treatment that deals with specific symptoms of an overdose. Flumazenil can be prescribed as a particular antagonist (usually in hospitals). Hemodialysis proved to be ineffective.

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Additional Information

In the process of using Nitrazepam, patients are strictly prohibited from drinking beverages that contain alcohol. This medicine shouldn’t be used for extended periods of time, unless it is prescribed by your doctor. With renal or hepatic issues and lasting treatment, it is necessary to manage the levels of hepatic enzymes.

Healing with Nitrazepam should be stopped when patients acquire such abnormal reactions as increased hostility, excitation, panic, suicidal behavior, hallucinations, muscle cramps, problems with sleep or superficial sleep.

This drug should be used throughout pregnancy in exceptional situations and only for “vital” indications.

During the usage of Nitrazepam (Mogadon), the patient should be extremely cautious when driving means of transportation and engaging in other potentially harmful activities that necessitate an increased focus and speed of reactions.

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Lunesta (eszopiclone) possesses hypnotic effect, makes part from the medicine called sedatives. It manages sleep problems through direct action on the balance of brain chemicals. This drug is primarily used for management of insomnia. Lunesta causes sedation to help the patient fall asleep more efficiently and exclude nocturnal awakenings.

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Prior to administration of the drug

This medicine is quite efficient. Don’t use this drug throughout your regular waking hours. Plan its administration in a way that allows you to rest for about 8 hours.

There is a high probability for people to have no recollection of events like eating or driving wherever they use this medicine. It is highly recommended to interrupt treatment and reach to your physician for a further consultation.

Patients that experience allergic reactions to eszopiclone should also consult a doctor before administration.

For safety reasons, you should talk to your physician whether you have:

  • Problems with liver;
  • Troubles breathing;
  • History associated with mental illnesses or suicidal behavior;
  • Addiction to drugs or alcohol.

buy lunesta onlineThere is no clear evidence that would suggest that Lunesta is able to affect the pregnancy. If you have any concerns regarding the administration of this medicine, be sure to consult with your doctor.

Lunesta has demonstrated a stronger sedative in the course of treatment for older patients. Unintentional falls are not uncommon in elderly people who use medication of this kind. It is important to be cautious when administrating this medicine in order to avoid situations in which you might get injured.

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Administration of Lunesta

The patient shouldn’t deviate in any way from the prescribed dosage. This drug is to be used for short-term treatment purposes. The leaflet included with the medicine provides the necessary directions.

Lunesta is able to form dependence. This medicine must not be shared with other people, especially with those who have been involved in episodes of drug and alcohol abuse. Keep the drug in an unreachable place for children.

For better absorption of this medicine, it is important to avoid its administration within an hour following a heavy meal.

buy lunesta onlineInform your physician whether your illness manifestations have not improved during a week of treatment or whether they got worse.

Sudden withdrawal from Lunesta is able to case withdrawals symptoms. In order to avoid that, the patients should do it gradually, in a period of a few days. Ask your doctor for more data prior to stopping taking the drug.

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Things to look for while using Lunesta

Drinking alcohol is strongly forbidden during treatment with Lunesta. There is a high possibility for occurrence of dangerous adverse effects.

During long travels you should avoid using this medicine because there is a chance that you will be bothered before the action of the drug wears off. Short episodes of forgetfulness can become common if you fail to get a minimum of 7 hours of sleep after the administration of this drug.

where to buy lunesta online?Eszopiclone is able to be the cause for adverse effects that may influence your thoughts and reactions. There is a possibility that you will feel drowsy even the morning after you’ve taken this medicine. The patient should be aware of how this drug influences him in case that he has to manage heavy equipment, drive a vehicle, or deal with anything that involves him to stay extremely focused.

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Adverse effects of Lunesta

Look out for any manifestations of severe allergic reactions cause by this drug. Get an immediate medical help or contact your doctor if you experience the following: rash; vomiting; trouble breathing; inflammation of certain parts of your face.

Contact your doctor in case you experience:

  • nervousness, sadness, hostility, anxiety;
  • memory impairment, abnormal thoughts or actions;
  • reflecting upon committing harmful actions to yourself;
  • uncertainty, strange visions and sounds.

The most frequently encountered side effects may expressed through:

  • day-time sleepiness, lightheadedness;
  • headache;
  • abnormal or repulsive taste in your mouth;
  • manifestations suggesting that you have a cold, like sore throat or stuffed nose.

The list of adverse effects is not complete. Contact your doctor to find out more about potential harmful effects that Lunesta may manifest on your body.

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Additional information

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Lunesta is capable of causing strong allergic reaction. You should stop the administration of this drug whether you experience unusual swelling, rash or problems involving your breathing. Such symptoms require immediate medical attention. Administrating this drug during your working hours may be potentially dangerous, if you are involved in an activity that requires focus and attention.

Short-term memory loss may occur for less significant events if you have taken the medicine at the wrong time. This would require you to consult your doctor and interrupt the treatment, if necessary. There may be another medicine that would be more suitable for your particular case.

It is important to identify the exact way Lunesta affects your ability to work and interact in your usual medium. Potentially hazardous work should be excluded during the period of your treatment, as well as any other activities that require you to stay awake at all times.

This medicine does not interact well with alcoholic beverages. Alcohol may enhance the effects of this medicine. Keep this drug away from people who had history with abuse of substances.

Keep Lunesta in an unreachable place for children and other people.

Interrupting the course of treatment in an abrupt manner may cause the appearance of withdrawal syndrome, which is characterized through unpleasant symptoms. The right way to stop the administration of Lunesta is to gradually decrease the dose in a span of few days. For more information regarding the usage of this drug and its interaction with other medicine, consult your doctor or a specialist in the field of mental illnesses.

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Buying Imovane Online – Order Zopiclone Without Prescription

Imovane (zopiclone) is a part of psychotropic and cyclopyrrolones class medications, which are structurally dissimilar to benzodiazepines and barbiturates. This medicine possesses an effective hypnotic action.

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Clinical Effect

It rapidly causes sleep with a normal phase composition; in the morning there is no sleepiness and weakness. Impaired renal function does not require a dose reduction. Abrupt withdrawal does not cause adverse effects.

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Indication of Use for Imovane

Sleep problems: sleep deprivation, nocturnal awakenings, hasty awakening, secondary sleep disturbances in mental disorders.

Dosing and Administration

The advised dose represents 1 tablet which is 7,5 mg Imovane. It should be administered shortly before bed time. The patient can increase the dose up to 2 tablets in case of severe or constant insomnia.

Treatment of aged patients has to begin with a lesser dosage of 3,75 mg.

In relation to the efficiency and tolerability, the prescribed amount can be increased in the future.

Dysfunction of the kidney does not require a cut in the dose of Imovane.

For people experiencing hepatic insufficiency, the suggested quantity of Imovane is 3,75 mg.


  • Myasthenia gravis;
  • Sleep apnea condition;
  • Age under 18;
  • Acute respiratory syndrome;
  • Acute hepatic impairment;
  • Allergic reaction to the active components of the medicine.

Treatment using Imovane has to be avoided during pregnancy and breast-feeding.

Side effects

Most often encountered adverse effects that result from use of Imovane are:

  • dry mouth,
  • lightheadedness,
  • headache,
  • residual sleepiness after awakening,
  • anterograde amnesia is possible,
  • rarely – nightmarish dreams,
  • irritability or confusion,
  • hallucinations,
  • depressed mood and aggressiveness,
  • impaired synchronization of movements,
  • inadequate actions with possible occurrence of amnesia,
  • dyspepsia,
  • vomiting,
  • a slight increase in the activity of hepatic transaminases and/or AP in the blood serum,
  • itchiness,
  • anaphylactic reactions,
  • withdrawal syndrome,
  • nervousness,
  • tremor,
  • excessive perspiration,
  • anxiety,
  • tachycardia,
  • very infrequently – seizures.

Interaction with Other Medicine

Imovane diminishes the concentration of trimipramine. This medication enhances the action of alcohol and other drugs which depress the central nervous system.

Imovane Overdose

Signs and symptoms include a diverse degree of CNS depression, varying from sleepiness to coma, depending on the amount of the drug that was taken. In mild cases, there is tiredness, confusion, apathy. In more serious cases – ataxia, low blood pressure, respiratory depression and coma.

Overdosing does not pose danger to life except if it is combined with the use of other drugs that have a depressing effect on the central nervous system. Other risk factors, such as concomitant disease or a weakened patient, may exacerbate symptoms and even (very rarely) cause death.

Treatment would include: gastric lavage is effective only if performed shortly after administration of the drug. If necessary, symptomatic and supportive therapy in a hospital is recommended. Effort should be made to maintain the respiratory and cardiovascular system. Flumazenil can be used as a type of an antidote.

Precautionary measures

The next day after administration, you should be really careful if you are going to drive vehicles and operate potentially hazardous mechanisms and machinery. Prolonged use, like in the case with other sleeping pills, should be avoided. It is required to stay away from simultaneous use with alcohol and medicine that depresses the CNS.

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Dormicum (midazolam) possesses an efficient tranquilizer and hypnotic action. The medicine is also characterized through an anxiolytic, anticonvulsant and relaxant effect. Following the use of this medicine, the patient may not remember the last events that occurred throughout the most intense action of the active substance. Where to Buy Dormicum (Midazolam) Online? In Our Online Pharmacy!

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  • Sedation with preservation of consciousness before physical investigations or medical procedures, produced under local anesthesia or without it.
  • Premedication before anesthesia.
  • As an induction agent for inhaled anesthetics or as a sedative for combined anesthesia, including total intravenous anesthesia.
  • Ataralgesia together with ketamine for children (intramuscularly).
  • Prolonged sedation in intensive care.

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  • Allergic reaction to benzodiazepines or to any component of the drug.
  • Pregnancy and breast-feeding

Benzodiazepines are not recommended for use during pregnancy, unless they have a safer alternative. The use of the drug in the last trimester of pregnancy or in large doses during the first stage leads to perturbations of the heart rhythm in the fetus, hypotension, hypothermia and mild respiratory depression in the newborn. Additionally, in children, whose mothers in the late period of pregnancy have been receiving benzodiazepines for a long time, a physical addiction may be formed with a certain risk of the withdrawal syndrome in the postnatal period. Dormicum does penetrate the breast milk.

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Dormicum Adverse Effects

The list of most frequent adverse effects of Dormicum includes:

  • Drowsiness,
  • Long sedation,
  • Confusion,
  • Euphoria,
  • Hallucinations,
  • Weakness,
  • Headache,
  • Lightheadedness,
  • Anterograde amnesia (length of which is directly connected to the dosage),
  • Hyperactivity,
  • Hostile behavior,
  • Irritation,
  • Muscle tremor,
  • Excitatory paroxysms,
  • Sickness,
  • Vomiting,
  • Hiccough,
  • Constipation,
  • Hypotension,
  • Tachycardia,
  • Dry mouth
  • Dyspnea,
  • Skin rash,
  • Hives,
  • Itching.

The use of Dormikum, even in curative doses, may result in the formation of physical addiction. The abandonment of the medicine, especially abrupt, after a long intravenous use, may be complemented by a withdrawal syndrome, symptoms of which would include seizures.

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Mode of application

Dormicum is a strong tranquilizer that calls for slow administration and individual dose prescription.

In case of older patients (60 and older), the dose should be cautiously chosen, taking into account the unique factors inherent in each patient.

The dose of Dormicum is selected individually; the drug cannot be injected quickly. The beginning of sedation varies in each case in relation to the patient’s state and dosing regimen that would include rate of administration and dose size. If needed, the dosage is selected individually. The effect occurs approximately two minutes after injection, while the maximum effect is reached on average, after 2,4 minutes.

The medicine is administered intramuscularly in a dose of 0,1 – 0,15 mg per kg for five to ten minutes prior a procedure/operation. Patients in a state of more pronounced excitation can be administered up to 0,5 mg per kg of body weight. Usually, a dose of 10 mg is enough and there is no need to exceed it.

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Dormicum Overdose

Signs of an overdose for Dormicum are expressed, mostly, in the intensification of its clinical effects: sleepiness, confusion, stupor and muscle weakness or paradoxical arousal. Similarly to an episode of overdose with other benzodiazepines, this does not present any danger, except the patient simultaneously received other drugs depressing the CNS or alcohol. More serious symptoms include areflexia, low blood pressure, cardiovascular depression and respiratory depression, respiratory arrest and, sometimes, coma.

Generally, only vital functions need to be observed. If a case of overdose occurs during treatment, special attention should be paid to intensive therapy aimed at maintaining cardiovascular and respiratory activity. Overdose incidents can be suppressed by a benzodiazepine antagonist – Anexam (active substance – flumazenil).

Impact on driving and operating machinery

Sedation, memory loss, lack of attentiveness and impaired muscle function can negatively affect the capability to drive a car or work with machinery. Do not deal with vehicles or work with machines or any potentially harmful mechanisms until the action of the drug is completely eliminated.

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Buy Ambien (Zolpidem) Online

Ambien possesses sedative action. This drug improves the intervals of falling asleep, decreases the number of nocturnal awakenings and improves the entire duration of sleep and its quality. It extends the second stage of sleep and the stage of deep sleep (third and fourth). Ambien doesn’t produce sleepiness during the day.

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  • Acute and/or severe respiratory impairment;
  • Severe or chronic liver failure;
  • Nocturnal sleep apnea;
  • Lactose intolerance;
  • Pregnancy;
  • Breast-feeding;
  • Patients under the age of 18;
  • Hypersensitivity to Ambien or any other components of the drug.

It is necessary to prescribe Ambien therapy with caution to patients with respiratory failure, hepatic insufficiency, depressive disorder, alcoholism, drug and other addictions.

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Dosage and Administration

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Ambien is administered right before bed time in a single take of 10 mg.

Treatment should begin with a dose of 5 mg for those patients who experience problems with liver or for elderly patients. If there is insufficient effect and the patient has good tolerability of Ambien, the dosage can be increased to 10 mg. The maximum daily dose is 10 mg. The period of treatment should not go above 4 weeks. With transient insomnia, the recommended period of treatment is 2-5 days, with a situational course – 2-3 weeks.

Short duration of treatment doesn’t call for a slow withdrawal of the drug. When the drug is being used for a long period of time, the risk of development insomnia increases, in which case the withdrawal should be carried out slowly (a gradual decrease in the daily dosage).

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Adverse Effects of Ambien

The most commonly experienced side effects for patients who are using Ambien include:

  • Impaired vision;
  • Taste distortion;
  • Ataxia;
  • Confusion;
  • Euphoria;
  • Insomnia;
  • Dizziness.

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Some of the less common adverse effects include:

  • Increased sweating;
  • Cardiovascular diseases (hypertension, tachycardia);
  • Agitation;
  • Decreased cognitive ability;
  • Difficulty concentrating;
  • Hallucinations;
  • Migraine;
  • Drowsiness;
  • Tremor;
  • Constipation;
  • Arthritis;
  • Hyperglycemia;
  • Bronchitis.

Adverse effects which have the minimal rate of occurrence include:

  • Glaucoma;
  • Hypotension;
  • Allergic reaction;
  • Abdominal pain;
  • Face swelling;
  • Restless legs syndrome;
  • Weight loss;
  • Arrhythmia;
  • Circulatory disorders;
  • Hypertension;
  • Varicose veins;
  • Hostile behavior;
  • Decreased libido;
  • Hypotension;
  • Panic attacks;
  • Somnambulism;
  • Suicidal behavior;
  • Gastritis;
  • Tendonitis;
  • Frequent urination;
  • Acne dermatitis.

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Special instructions

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Preservation of insomnia within 7-14 days of treatment indicates the presence of primary mental disorders and/or disorders of the nervous system. Therefore, in order to identify these disorders, the patient’s condition must be reassessed on a regular basis.

When Ambien is used, mental and behavioral reactions may occur. The risk of developing such responses is higher in elderly patients. If such reactions occur, the drug has to be discontinued. After the course of treatment that lasts for several weeks, there may be observed reduction in the sedative and hypnotic action of the drug.

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The use of Ambien (especially for a long time) can lead to the formation of physical and/or mental dependence, the chances of which increase in proportion to the dosage and length of treatment, as well as in patients with a history of alcohol abuse or other drugs and non-medicinal substances. Such patients should be closely monitored during the treatment period. However, dependence (extremely rare) can occur with the use of therapeutic doses and/or in patients without individual risk factors.

The combination with benzodiazepines increases the risk of drug dependence.

In elderly patients or with a violation of liver function, a significant increase in the half-life of Ambien may occur, which may lead to cumulation of the drug when it is repeated. Based on the peculiarities of Ambien pharmacokinetics, in case of chronic renal failure, cumulation of the drug is not expected.

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When elderly people are using Ambien, care must be taken in connection with the chance of development of severe sedative and/or muscle relaxant effects.

During the treatment period, one should refrain from engaging in potentially dangerous activities that require increased concentration of attention (driving, working with mechanisms), and the speed of psychomotor reactions.

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Interaction with Other Drugs

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Alcohol enhances the sedative action of Ambien, and it is not recommended to use at the same time during treatment.

Drugs that possess a depressive effect on the CNS (neuroleptics, barbiturates, other sleeping pills, anxiolytics/sedatives, antidepressants with sedative action, narcotic analgesics, antitussive of central action), antiepileptic drugs, general anesthetics, antihistamines with sedative effect, antihypertensive central action; baclofen; thalidomide; Pizotifen, when combined, there is an intensification of the oppressive action on the CNS and the chance of respiratory depression increases;

  • Buprenorphine increases the chance of respiratory depression;
  • Ketoconazole reduces the clearance of zolpidem, in connection with which it is possible to increase its sedative effect;
  • Itraconazole produces a slight, clinically insignificant change in the pharmacokinetics and pharmacodynamics of Ambien.

Rifampicin accelerates metabolism, reduces the concentration and effectiveness of Ambien.

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